Oxidant-Resistant LRRC8A/C Anion Channels Support Superoxide Production by Nox1
J. Rohrbough, H. Choi, H.-N. Nguyen, A. Dikalova, F. S. Lamb
This study shows that LRRC8A/C anion channels regulate Nox1-mediated superoxide production and TNF signaling in vascular smooth muscle cells, with LRRC8C being more resistant to oxidants than LRRC8D.
bioRxiv · Feb 3, 2021 · PreprintCell Biology