Author

J. Rosain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

A. Bousfiha· 2 shared D. Bogunovic· 2 shared F. Ailal· 2 shared J. Bustamante· 2 shared J.-L. Casanova· 2 shared L. Abel· 2 shared Y. Seeleuthner· 2 shared A. Cobat· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

A. Bousfiha

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel patient with inherited TNF deficiency and tuberculosis

N. Keating, M. Mesdaghi, Z. Chavoshzadeh, A. Karimi, M. Saberi, S. Unal, V. Meynier, C. Soudee, C. Laine, A. Solgi, S. Sharafian, A.-S. LHonneur, M. Migaud, Y. Seeleuthner, A. Cobat, , Stephanie Boisson-Dupuis

The paper reports three patients with inherited TNF deficiency who developed tuberculosis, showing TNF's essential role in immunity against M. tuberculosis.

medRxiv · Nov 9, 2026 · PreprintGenetic & Genomic Medicine

Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria

R. Yang, F. Mele, L. Worley, D. Langlais, J. Rosain, I. Benhsaien, H. Elarabi, C. A. Croft, J.-M. Doisne, P. Zhang, M. Weisshaar, D. Jarrossay, D. Latorre, Y. Shen, J. Han, , L. H Glimcher

This study identifies T-bet deficiency as a cause of mycobacterial disease by impairing IFN-γ production in innate and innate-like adaptive lymphocytes.

bioRxiv · Aug 31, 2020Immunology

Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy

C. N. Gruber, M. Martin-Fernandez, F. Ailal, X. Qiu, J. Taft, J. Altman, J. Rosain, S. Buta, A. Bousfiha, J.-L. Casanova, J. Bustamante, D. Bogunovic

The paper identifies a homozygous STAT2 mutation causing type I interferonopathy by disrupting USP18 interaction and signal termination.

bioRxiv · Dec 12, 2019Immunology