Mayaro virus replication restriction and induction of muscular inflammation in mice are dependent on age and type-I interferon response
C. M. Figueiredo, R. L. S. Neris, D. Gavino-Leopoldino, J. S. Almeida, J. S. Dos-Santos, C. P. Figueiredo, M. Bellio, M. T. Bozza, I. Assuncao-Miranda
This study investigates how age and type-I interferon response influence Mayaro virus replication and muscle inflammation in mice, showing adaptive immunity's role in viral clearance and inflammation in specific genetic backgrounds.
bioRxiv · Apr 9, 2019Microbiology