Ketamine's pharmacogenomic network in human brain contains sub-networks associated with glutamate neurotransmission and with neuroplasticity
G. A. Higgins, S. K. Handelman, A. Allyn-Feurer, A. Ade, J. S. Burns, G. S. Omenn, B. D. Athey
The paper identifies sub-networks within the ketamine pharmacogenomic network in the human brain associated with glutamate neurotransmission, neuroplasticity, and pharmacokinetics.
bioRxiv · Apr 28, 2020 · PreprintPharmacology & Toxicology