Chitinase 3-like-1 Stimulates PD-L1 and Other Immune Checkpoint Inhibitors
B. Ma, B. Akosman, S. Kamle, C.-M. Lee, J. S. Koo, C. G. Lee, J. A. Elias
This study shows Chi3l1 promotes PD-L1 and other immune checkpoint inhibitors in melanoma, suggesting combined targeting of Chi3l1 and PD-1-PD-L1 as a therapeutic strategy for pulmonary metastasis.
bioRxiv · Jan 15, 2021 · PreprintCancer Biology