Author

J. Spiriti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

D. M. Zuckerman· 2 shared J. Conway· 1 shared M. Wu· 1 shared R. Palli· 1 shared S. R. Subramanian· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

D. M. Zuckerman

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2 papers

Recent·Most cited

Should virus capsids assemble perfectly? Theory and observation of defects

J. Spiriti, J. Conway, D. M. Zuckerman

The paper quantifies conditions for viral capsid defects using a statistical mechanics model and confirms ~15% defective particles in cryoEM studies.

bioRxiv · Mar 14, 2020Biophysics

Middle-way flexible docking: Pose prediction using mixed-resolution Monte Carlo in estrogen receptor α

J. Spiriti, S. R. Subramanian, R. Palli, M. Wu, D. M. Zuckerman

This paper introduces a flexible docking method for protein-ligand interactions using mixed-resolution Monte Carlo, showing improved performance over existing methods for estrogen receptor α.

bioRxiv · Jan 8, 2019Biophysics