Author

J. Stuckey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

A. L. Garner· 1 shared A. Menon· 1 shared A. Nazzari· 1 shared A. S. Olia· 1 shared A. Schon· 1 shared B. Zhang· 1 shared D. D. Ho· 1 shared E. L. Cardenas· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. L. Garner

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Author profile →

2 papers

Recent·Most cited

Design of Cell-Permeable Inhibitors of Eukaryotic Translation Initiation Factor 4E (eIF4E) for Inhibiting Aberrant Cap-Dependent Translation in Cancer

E. L. Cardenas, R. L. O'Rourke, A. Menon, J. Meagher, J. Stuckey, A. L. Garner

This study designs cell-permeable inhibitors of eIF4E to block cap-dependent translation in cancer by using an acyclic nucleoside phosphonate prodrug strategy.

bioRxiv · May 23, 2023Cancer Biology

Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

T. Zhou, Y. Tsybovsky, A. S. Olia, J. Gorman, M. A. Rapp, G. Cerutti, G.-Y. Chuang, P. S. Katsamba, A. Nazzari, J. M. Sampson, A. Schon, P. D. Wang, J. Bimela, W. Shi, I.-T. Teng, , P. D. Kwong

This paper uses cryo-EM to show how SARS-CoV-2 spike protein undergoes pH-dependent structural changes that affect ACE2 binding and antibody evasion.

bioRxiv · Jul 4, 2020 · PreprintImmunology