Platelets fuel the inflammasome activation of innate immune cells
V. Rolfes, L. S. Ribeiro, I. Hawwari, L. Buotcher, N. S. Rosero, S. Maasewerd, M. L. S. Santos, S. V. Schmidt, M. Rothe, J. Stunden, L. H. Carvalho, C. J. Fontes, T. Prochnicki, M. Arditi, E. Latz, B. S. Franklin
This study shows platelets enhance inflammasome activation in immune cells, increasing IL-1β production, and identifies a platelet gene signature linked to autoinflammatory diseases.
bioRxiv · Oct 11, 2019Immunology