Pretreatment with yeast derived complex dietary-polysaccharide leads to suppressed gut inflammation, altered microbiota composition and increased immune regulatory short-chain fatty acid production in C57BL/6 mice
R. Gudi, J. Suber, R. Brown, B. Johnson, C. Vasu
This study shows that pretreatment with yeast-derived beta-glucans reduces DSS-induced colitis in mice by altering gut microbiota and increasing SCFA production, but loses efficacy when administered during disease onset.
bioRxiv · Oct 15, 2019 · PreprintImmunology