The effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model
M. M. Acosta, D. Sim, J. T. Bram, A. F. Read
This study investigates how drug dose and timing affect resistance emergence in a malaria model, finding that higher doses can increase resistance and timing impacts resistance risk non-linearly.
bioRxiv · Jan 27, 2020Evolutionary Biology