De novo designed Hsp70 activator dissolves intracellular condensates
J. Z. Zhang, N. Greenwood, J. Hernandez, J. T. Cuperus, B. Huang, B. D. Ryder, C. Queitsch, J. E. Gestwicki, D. Baker
The paper designs Hsp70 activators that dissolve intracellular condensates by modulating Hsp70 ATPase activity and promoting protein refolding.
bioRxiv · Sep 18, 2023 · PreprintBiochemistry