Cancer BiologybioRxiv
Development of a Cx46 targeting strategy for cancer stem cells
E. E. Mulkearns-Hubert, L. A. Torre-Healy, D. J. Silver…·J. D. Lathia
This study identifies clofazimine as a Cx46 inhibitor that targets glioblastoma cancer stem cells by disrupting gap junction communication, enhancing the efficacy of temozolomide.
DOI 10.1016/j.celrep.2019.03.079