Dedifferentiation alters chondrocyte nuclear mechanics during in vitro culture and expansion
S. Ghosh, A. K. Scott, B. Seelbinder, J. E. Barthold, B. M. S. Martin, S. Kaonis, S. E. Schneider, J. T. Henderson, C. P. Neu
This study shows that dedifferentiated chondrocytes exhibit altered nuclear mechanics and gene expression of nuclear envelope proteins, which may contribute to further dedifferentiation.
bioRxiv · Apr 26, 2021Biophysics