Biosynthesis of Strained Amino Acids Through a PLP-Dependent Enzyme via Cryptic Halogenation
M. B. Sosa, J. T. Leeman, L. J. Washington, H. V. Scheller, M. C. Y. Chang
The paper discovers the biosynthetic pathway for the non-canonical amino acid pazamine, involving a radical halogenase and a PLP-dependent enzyme, and shows its potential agricultural applications.
bioRxiv · Dec 13, 2023 · PreprintBiochemistry