Author

J. T. Yurkovich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:E. coli· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. O. Palsson· 3 shared L. Yang· 2 shared N. Mih· 2 shared A. Drager· 1 shared A. Feist· 1 shared A. V. Sastry· 1 shared B.-K. Cho· 1 shared C. Dalldorf· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

B. O. Palsson

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Author profile →

4 papers

Recent·Most cited

BioengineeringbioRxivJul 19, 2021

Data-Driven Strain Design Using Aggregated Adaptive Laboratory Evolution Mutational Data

P. V. Phaneuf, D. C. Zielinski, J. T. Yurkovich…·A. Feist

This paper presents a data-driven workflow to design microbial strains using aggregated ALE mutational data, revealing gene-centric mutations that significantly alter cellular states.

DOI 10.1021/acssynbio.1c00337

E. colistatistical model

𝕏 PostBluesky

BiochemistrybioRxivOct 14, 2019

The temperature dependence of platelet metabolism

F. Johannsson, J. T. Yurkovich, S. Guthmundsson…·O. Rolfsson

This study investigates how temperature affects platelet metabolism using metabolomics and systems biology, finding that oxidative metabolism is more temperature-sensitive than glycolysis.

DOI 10.3390/metabo14020091

humanmetabolomics

𝕏 PostBluesky

MicrobiologybioRxivJun 11, 2018

Systematic discovery of uncharacterized transcription factors in Escherichia coli K-12 MG1655

Y. Gao, J. T. Yurkovich, S. W. Seo…·B. O. Palsson

This study identifies and characterizes 16 uncharacterized transcription factors in E. coli K-12 MG1655 using computational prediction and experimental validation.

DOI 10.1093/nar/gky752

E. coliChIP-seq

𝕏 PostBluesky

MicrobiologybioRxivMar 6, 2018

The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

K. S. Choudhary, N. Mih, J. Monk…·B. O. Palsson

The paper classifies S. aureus strains based on AgrAC TCS genomic arrangements, linking agr types to virulence factor presence and protein structural properties.

DOI 10.3389/fmicb.2018.01082

humanwhole-genome sequencing

𝕏 PostBluesky