Traumatic brain injury-induced fear generalization in mice involves hippocampal memory trace dysfunction and is alleviated by (R,S)-ketamine
J. C. McGowan, L. R. Ladner, C. X. Shubeck, J. Tapia, C. T. LaGamma, A. Anqueira-Gonzalez, A. DeFrancesco, B. K. Chen, H. C. Hunsberger, E. J. Sydnor, R. W. Logan, T.-S. Yu, S. G. Kernie, C. A. Denny
This study shows that traumatic brain injury in mice causes fear generalization through hippocampal memory trace dysfunction, which is reduced by (R,S)-ketamine.
bioRxiv · Feb 24, 2023Animal Behavior & Cognition