Author

J. Tegner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Research Focus:differential expression· 2

Frequent Co-Authors

D. Gomez-Cabrero· 4 shared F. Prosper· 4 shared A. Vilas-Zornoza· 3 shared B. Paiva· 3 shared B. Saez· 3 shared D. Alignani· 3 shared I. Cenzano· 3 shared P. San Martin-Uriz· 3 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersCancer Biology

D. Gomez-Cabrero

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling

L. Sudupe, E. Muinos-Lopez, A. R. Lopez-Perez, A. Vilas-Zornoza, S. Sarvide, P. Ripalda-Cemborain, P. Aguirre-Ruiz, P. San Martin-Uriz, M. Larrayoz, L. Alvarez-Gigli, M. Abengozar-Muela, I. Cenzano, M. Cocera, J. Ruiz, I. Sancho Gonzalez, , F. Prosper

This study uses spatial transcriptomics to analyze bone marrow in MM mouse models and patients, revealing altered T-cell distribution, neutrophil traps, and inflammatory signaling in MM.

bioRxiv · Jul 3, 2024 · PreprintCancer Biology

Stromal and Endothelial Transcriptional Changes during progression from MGUS to Myeloma and after Treatment Response

I. Cenzano, M. Cocera, M. Larrayoz, L. Campos-Dopazo, S. Sanz, A. Bantan, A. Vilas, P. San-Martin, P. Aguirre-Ruiz, D. Alignani, A. Lopez, I. Sancho Gonzalez, J. Ruiz, P. Ripalda-Cemborain, M. Abengozar-Muela, , F. Prosper

This study identifies transcriptional changes in stromal and endothelial cells during MGUS to myeloma progression and treatment response, revealing a tumor-permissive BME signature that is modulated by therapy.

bioRxiv · Apr 24, 2024Cancer Biology

Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia

N. Planell, X. Martinez-de-Morentin, D. Mouzo, D. Lara-Astiaso, A. Vilas-Zornoza, P. San Martin-Uriz, D. Alignani, B. Paiva, A. Maillo, A. Kurowska, N. Berastegui, P. Garcia-Olloqui, A. Urdangarin, P. Noori, A. Ortega-Legarreta, , D. Gomez-Cabrero

This study characterizes the gene regulatory network of early human B-cell development and identifies regulatory elements linked to B-cell acute lymphoblastic leukemia.

bioRxiv · Jul 1, 2023 · PreprintImmunology

Genetic architecture of behavioural resilience to ocean acidification

R. Lehmann, C. Schunter, M. J. Welch, S. T. Arold, G. E. Nilsson, j. tegner, P. L. Munday, T. Ravasi

The paper identifies genetic variants associated with behavioural resilience to ocean acidification in a coral reef fish using whole-genome scans.

bioRxiv · Oct 18, 2022 · PreprintEcology

Deep deconvolution of the hematopoietic stem cell regulatory microenvironment reveals a high degree of specialization and conservation between mouse and human.

J. Ye, I. A. Calvo, I. Cenzano, A. Vilas-Zornoza, X. Martinez-de-Morentin, M. Lasaga, D. Alignani, B. Pavia, A. C. Vinado, P. San Martin-Uriz, J. P. Romero, D. Quilez Agreda, M. MinanaBarrios, I. Sancho-Gonzalez, G. Todisco, , D. Gomez-Cabrero

The paper develops a bioinformatic pipeline to analyze scRNA-seq data and identifies intermediate cell states and differentiation stages in the hematopoietic stem cell regulatory microenvironment, revealing conservation between mouse and human.

bioRxiv · Jul 17, 2021 · PreprintImmunology