Author

D. Lara-Astiaso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

A. Vilas-Zornoza· 4 shared F. Prosper· 4 shared T. Ezponda· 3 shared B. Paiva· 2 shared D. Alignani· 2 shared D. Gomez-Cabrero· 2 shared J. I. Martin-Subero· 2 shared J. P. Romero· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersCancer Biology

A. Vilas-Zornoza

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia

N. Planell, X. Martinez-de-Morentin, D. Mouzo, D. Lara-Astiaso, A. Vilas-Zornoza, P. San Martin-Uriz, D. Alignani, B. Paiva, A. Maillo, A. Kurowska, N. Berastegui, P. Garcia-Olloqui, A. Urdangarin, P. Noori, A. Ortega-Legarreta, , D. Gomez-Cabrero

This study characterizes the gene regulatory network of early human B-cell development and identifies regulatory elements linked to B-cell acute lymphoblastic leukemia.

bioRxiv · Jul 1, 2023 · PreprintImmunology

Transcriptional regulation of HSCs in Aging and MDS reveals DDIT3 as a Potential Driver of Dyserythropoiesis

N. Berastegui, M. Ainciburu, J. P. Romero, A. Alfonso-Pierola, C. Philippe, A. Vilas-Zornoza, P. San Martin, R. Ordonez, D. O. Alignani, S. Sarvide, L. Castro, J. M. Lamo-Espinosa, M. San-Julian, T. Jimenez, F. Lopez Cardenas, , F. Prosper

This study identifies DDIT3 as a driver of dyserythropoiesis in MDS by showing its upregulation in HSCs and its ability to disrupt erythropoiesis when overexpressed.

bioRxiv · Sep 8, 2021 · PreprintCancer Biology

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

R. Ordonez, M. Kulis, N. Russinol, V. Chapaprieta, R. Beekman, C. Meydan, M. Duran-Ferrer, N. Verdaguer-Dot, G. Clot, R. Vilarrasa-Blasi, L. Garate, E. Miranda, A. Carrasco, T. Ezponda, A. Vilas-Zornoza, , J. I. Martin-Subero

The paper identifies aberrant chromatin activation as a common mechanism driving the malignant phenotype in multiple myeloma.

bioRxiv · Aug 20, 2019Cancer Biology

Single-cell RNA-seq analysis reveals the crucial role of Collagen Triplex Helix Repeat Containing 1 (CTHRC1) cardiac fibroblasts for ventricular remodeling after myocardial infarction

A. Ruiz-Villalba, J. P. Romero, S. C. Hernandez, A. Vilas-Zornoza, N. Fortelny, L. Castro, P. San Martin-Uriz, E. Lorenzo-Vivas, P. Garcia-Olloqui, M. Palacios, J. J. Gavira, G. Bastarrika, S. Janssens, E. Iglesias, G. Abizanda, , F. Prosper

This study identifies a pro-fibrotic fibroblast subpopulation in mice after myocardial infarction, showing CTHRC1's role in ventricular remodeling and cardiac function.

bioRxiv · May 20, 2019Cell Biology