PiggyBac Transposase Mediated Inducible Trophoblast-specific Knockdown of Mechanistic Target of Rapamycin in Mice Decreases Placental Nutrient Transport and Inhibits Fetal Growth.
F. J. Rosario, J. Urschitz, H. Razavy, M. Elston, T. L. Powell, T. Jansson
This study knocks down mTOR in trophoblasts of late pregnant mice, reducing placental nutrient transport and fetal growth.
bioRxiv · Feb 20, 2024 · PreprintPhysiology