Can pseudotopological models for SMC-driven DNA loop extrusion explain the traversal of physical roadblocks bigger than the SMC ring size?
B. Pradhan, R. Barth, E. Kim, I. F. Davidson, J. v. d. Torre, J.-M. Peters, C. Dekker
This study evaluates pseudotopological models of SMC-driven DNA loop extrusion and finds they conflict with experimental data on roadblock traversal.
bioRxiv · Aug 2, 2022 · PreprintBiophysics