Author

J. W. Dowling

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Forero· 1 shared A. Karp· 1 shared J. R. Smith· 1 shared J. Schwerk· 1 shared R. Savan· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. Forero

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1 paper

Recent·Most cited

MEF2A suppresses replicative stress responses that trigger DDX41-dependent IFN production

J. R. Smith, J. W. Dowling, A. Karp, J. Schwerk, R. Savan, A. Forero

This study shows MEF2A suppresses type I IFN production by preventing R-loop accumulation and DDX41/STING pathway activation in response to replicative stress.

bioRxiv · Sep 15, 2022Immunology