Author

J. R. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Animal Behavior & Cognition· 1 Cell Biology· 1 Ecology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

R. Savan· 3 shared A. Forero· 2 shared J. Schwerk· 2 shared A. E. L. Stone· 1 shared A. Esnal-Zufiaurre· 1 shared A. Karp· 1 shared A. M. Kell· 1 shared A. Sinyagin· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersImmunology

R. Savan

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Local tree cover predicts mosquito species richness and disease vector presence in a tropical countryside landscape

J. E. Farner, M. E. Howard, J. R. Smith, C. B. Anderson, E. A. Mordecai

The paper examines how local tree cover affects mosquito species richness and disease vector presence in tropical landscapes, finding tree cover supports biodiversity and reduces vector presence at small spatial scales.

Landscape Ecology · May 28, 2025Peer-reviewedEcology

Mechanisms of octopus arm search behavior without visual feedback

D. M. Sivitilli, T. Strong, W. Weertman, J. Ullmann, J. R. Smith, D. H. Gire

This study investigates how octopuses search for prey in visually occluded spaces using contact-based strategies, revealing local sucker coordination as a key mechanism.

bioRxiv · Mar 13, 2023Animal Behavior & Cognition

MEF2A suppresses replicative stress responses that trigger DDX41-dependent IFN production

J. R. Smith, J. W. Dowling, A. Karp, J. Schwerk, R. Savan, A. Forero

This study shows MEF2A suppresses type I IFN production by preventing R-loop accumulation and DDX41/STING pathway activation in response to replicative stress.

bioRxiv · Sep 15, 2022Immunology

Cardiopulmonary bypass activates classical monocytes via shear-mediated activation of Store-Operated Calcium Entry

W. Li, L. N. Tu, L. Hsieh, J. R. Smith, Y.-T. Yeh, A. Sinyagin, M. Ghassemian, A. Timms, K. Charette, D. Mauchley, M. McMullan, L. Bohuta, C. Greene, M. Regier, J. C. del Alamo, , V. Nigam

The paper identifies SPTAN1 and RAF1 as genes activated by shear stress during cardiopulmonary bypass, leading to inflammation and cell death through store-operated calcium entry.

bioRxiv · May 4, 2022 · PreprintCell Biology

Endomembrane targeting of human OAS1 p46 augments antiviral activity

F. W. Soveg, J. Schwerk, N. S. Gokhale, K. Cerosaletti, J. R. Smith, E. Pairo-Castineira, A. M. Kell, A. Forero, S. A. Zaver, K. Esser-Nobis, J. Roby, T.-Y. Hsiang, S. Ozarkar, J. M. Clingan, E. T. McAnarney, , R. Savan

This study shows that the OAS1 p46 isoform, targeted to the endomembrane system, enhances antiviral activity against RNA viruses and is associated with COVID-19 severity.

bioRxiv · Apr 21, 2021Immunology

Single cell RNA sequencing redefines the mesenchymal cell landscape of mouse endometrium

P. M. Kirkwood, D. A. Gibson, J. R. Smith, J. R. Wilson-Kanamori, O. Kelepouri, A. Esnal-Zufiaurre, R. Dobie, N. C. Henderson, P. T. Saunders

This study uses single-cell RNA sequencing to redefine the mesenchymal cell landscape in mouse endometrium, identifying five subpopulations including pericytes, vascular smooth muscle cells, and three distinct fibroblast subtypes.

bioRxiv · Aug 20, 2020Physiology