A simulation framework for modeling the within-patient evolutionary dynamics of SARS-CoV-2
J. W. Terbot, B. S. Cooper, J. M. Good, J. D. Jensen
This study develops a simulation framework to model SARS-CoV-2 evolutionary dynamics within patients, identifying plausible models with severe infection bottlenecks and high rates of deleterious mutations.
bioRxiv · Jul 13, 2023Evolutionary Biology