Author

J. Witten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Alexander-Katz· 1 shared E. Zumbro· 1 shared K. Ribbeck· 1 shared N. Holten-Andersen· 1 shared S. C. Grindy· 1 shared W. G. Chen· 1 shared

Activity by Year

2016-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperBioengineering

A. Alexander-Katz

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2 papers

Recent·Most cited

Computational Insights Into Avidity of Polymeric Multivalent Binders

E. Zumbro, J. Witten, A. Alexander-Katz

This study uses Brownian dynamics simulations to show that longer multivalent polymers increase binding avidity to targets but reach a limit at high degrees of polymerization, and improve binding efficiency through inter-target interactions.

bioRxiv · Feb 8, 2019Bioengineering

Charge influences substrate recognition and self-assembly of hydrophobic FG sequences

W. G. Chen, J. Witten, S. C. Grindy, N. Holten-Andersen, K. Ribbeck

This study investigates how charge type and placement affect FG-domain self-assembly and substrate recognition in nucleoporins using synthetic peptides.

bioRxiv · Dec 12, 2016Biophysics