ImmunologybioRxiv
Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis
G. Mijnheer, N. H. Servaas, J. Y. Leong…·F. van Wijk
The paper identifies persistent, antigen-specific T cell clones in JIA joints and circulation, suggesting antigen-driven expansion of both Tregs and Teffector cells.
DOI 10.7554/elife.79016