Author

N. H. Servaas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Pandit· 2 shared A. Boltjes· 1 shared A. C. Hinrichs· 1 shared A. J. Affandi· 1 shared A. Ottria· 1 shared A. Petrelli· 1 shared C. G. K. Wichers· 1 shared C. P. J. Bekker· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

A. Pandit

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Author profile →

2 papers

Recent·Most cited

Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis

G. Mijnheer, N. H. Servaas, J. Y. Leong, A. Boltjes, E. Spierings, P. Chen, L. Lai, A. Petrelli, S. Vastert, R. J. De Boer, S. Albani, A. Pandit, F. van Wijk

The paper identifies persistent, antigen-specific T cell clones in JIA joints and circulation, suggesting antigen-driven expansion of both Tregs and Teffector cells.

bioRxiv · Feb 10, 2022Immunology

Nuclear receptor subfamily 4A signaling as a key disease pathway of CD1c+ dendritic cell dysregulation in systemic sclerosis

N. H. Servaas, S. Hiddingh, E. Chouri, C. G. K. Wichers, A. J. Affandi, A. Ottria, C. P. J. Bekker, M. Cossu, S. Silva-Cardoso, M. van der Kroef, A. C. Hinrichs, T. Carvalheiro, N. Vazirpanah, L. Beretta, M. Rossato, , A. Pandit

This study identifies NR4A nuclear receptor subfamily genes as key regulators of immune and fibrosis pathways in SSc cDC2s through transcriptomic and network analysis, with functional validation using ChIP-sequencing and in vitro experiments.

bioRxiv · Nov 8, 2021Immunology