Phosphorylation-dependent conformational change in the Keratin 19 head domain: Implications for filament assembly and binding to GSK3β and 14-3-3
Y. Ji, M. Jeong, J. Kim, J. Yeom, M. A. Han, C. Park, S.-H. Lee, E. Hong, Y. H. Ko, P. A. Coulombe, J. H. Kim, Chang-Hun Lee
This study identifies a phosphorylation-dependent conformational change in the K19 head domain that affects filament assembly and interactions with GSK3β, but not 14-3-3 proteins.
bioRxiv · Nov 9, 2026 · PreprintBiochemistry