Tetramerization of Phosphoprotein is essential for Respiratory Syncytial virus budding while its N terminal region mediates direct interactions with the Matrix protein.
M. Bajorek, M. Galloux, C.-A. Richard, O. Szekely, R. Rosenzweig, C. Sizun, J.-F. Elcouët
This paper identifies the tetrameric structure of the Phosphoprotein (P) as essential for RSV budding and shows its direct interaction with the Matrix (M) protein during assembly.
bioRxiv · Nov 17, 2020Microbiology