Author

J.-S. Fan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

D. Yang· 2 shared T. Xiao· 1 shared W. H. Lee· 1 shared W. Liu· 1 shared Y. Lu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

D. Yang

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2 papers

Recent·Most cited

Dengue virus protease activity modulated by dynamics of protease cofactor

W. H. Lee, W. Liu, J.-S. Fan, D. Yang

This study investigates the dynamic conformational equilibrium of the dengue virus NS3pro-NS2B complex and shows that proteolytic activity correlates with the population of the closed conformation.

bioRxiv · Nov 11, 2020Biophysics

Ligand Entry into Fatty Acid Binding Protein via Local Unfolding instead of Gap Widening

T. Xiao, Y. Lu, J.-S. Fan, D. Yang

This study shows that fatty acids enter FABP via local unfolding of helix 2, not gap widening, using a gap-closed variant and biophysical experiments.

bioRxiv · Sep 25, 2019Biophysics