Author

W. H. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Liu· 1 shared C. Glembotski· 1 shared D. Yang· 1 shared D. Yi· 1 shared H. Ding· 1 shared H. Miyamoto· 1 shared I. Singh· 1 shared J. Pan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperPhysiology

B. Liu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

E2F1 Mediates SOX17 Deficiency-Induced Pulmonary Hypertension

D. Yi, B. Liu, H. Ding, S. Li, R. Li, J. Pan, K. Ramirez, X. Xia, M. Kala, I. Singh, Q. Ye, W. H. Lee, R. Frye, T. Wang, Y. Zhao, , Z. Dai

This study shows that SOX17 deficiency in endothelial cells causes pulmonary hypertension via E2F1 signaling, suggesting E2F1 as a therapeutic target in PAH.

bioRxiv · Feb 15, 2023Physiology

Dengue virus protease activity modulated by dynamics of protease cofactor

W. H. Lee, W. Liu, J.-S. Fan, D. Yang

This study investigates the dynamic conformational equilibrium of the dengue virus NS3pro-NS2B complex and shows that proteolytic activity correlates with the population of the closed conformation.

bioRxiv · Nov 11, 2020Biophysics

Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells

Y. Kwon, S. B. Nukala, S. Srivastava, H. Miyamoto, N. I. Ismail, J. Rehman, S.-B. Ong, W. H. Lee, S.-G. Ong

This study shows that SARS-CoV-2 RNA can enter cardiomyocytes via extracellular vesicles from infected lung cells, leading to inflammation-related gene upregulation.

bioRxiv · May 14, 2020Cell Biology

Isolation and Characterization of a Rhizobium Bacterium Associated with the Toxic Dinoflagellate Gambierdiscus balechii

Z. WU, X. Yang, S. Lin, W. H. Lee, P. K. S. Lam

The paper isolates and characterizes a Rhizobium bacterium associated with the dinoflagellate Gambierdiscus balechii, showing it benefits from the association by utilizing extracellular organic matter.

bioRxiv · Oct 1, 2019 · PreprintMicrobiology