Synthesis of water-soluble and gastrointestinal transit-resistant FA-FOS conjugate for targeted delivery to the colon: pharmacokinetics, pharmacodynamics, efficacy
This paper synthesizes a water-soluble FA-FOS conjugate resistant to gastrointestinal transit, evaluates its pharmacokinetics, pharmacodynamics, and efficacy in delivering FA to the colon and tumors.
bioRxiv · May 5, 2023 · PreprintPharmacology & Toxicology