Key mutations on spike protein altering ACE2 receptor utilization and potentially expanding host range of emerging SARS-CoV-2 variants
Q. Wang, S.-B. Ye, Z.-J. Zhou, J.-Y. Li, J.-Z. Lv, B. Hu, S. Yuan, Y. Qiu, X.-Y. Ge
This study identifies key spike protein mutations in SARS-CoV-2 variants that enhance ACE2 receptor utilization across multiple animal species, potentially increasing host range and spillover risk.
bioRxiv · Apr 11, 2022Microbiology