Calmodulin acts as a chaperone during co-translational folding of the Kv7.2 channel Calcium Responsive Domain.
Arantza Muguruza‐Montero, Jack R. Tait, Sara M‐Alicante, Ane Metola, Eider Núñez, Janire Urrutia, Vanda Šunderlíková, Alexandros Katranidis, Gunnar von HEIJNE, Sander J. Tans, Álvaro Villarroel
This study shows calmodulin acts as a chaperone during co-translational folding of the Kv7.2 channel's calcium responsive domain by stabilizing metastable hairpins.
bioRxiv · Nov 15, 2024 · PreprintMolecular Biology