Author

Jack T. Crusher

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Chumin Zhou· 1 shared Eduard PetrosyaniD· 1 shared Eileen E. ParkesiD· 1 shared Ester M. HammondiD· 1 shared Graham Booker· 1 shared Kenneth Friesen· 1 shared Priya SamueliD· 1 shared Sophie A. TwiggeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Chumin Zhou

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1 paper

Recent·Most cited

HIF-1 regulated TPM3 links hypoxia to motility and invasion beyond the hypoxic fraction in triple-negative breast cancer

Chumin Zhou, Jack T. Crusher, Kenneth Friesen, Sophie A. Twigger, Eduard Petrosyan, Graham Booker, Priya Samuel, Eileen E. Parkes, Ester M. Hammond

This study identifies TPM3 as a HIF-1-regulated protein that enhances hypoxic TNBC cell motility and invasion, and shows its potential as a therapeutic target.

npj Breast Cancer · Mar 14, 2026Peer-reviewedCancer Biology