Author

Ester M. Hammond

University of OxfordORCID 0000-0002-2335-3146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Eileen E. ParkesiD· 2 shared A. CarteriD· 1 shared Alistair EastoniD· 1 shared Amber M. RidgwayiD· 1 shared Andréa E. TijhuisiD· 1 shared Antoine WallabrègueiD· 1 shared Benjamin IzariD· 1 shared Bruno BeernaertiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Eileen E. ParkesORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HIF-1 regulated TPM3 links hypoxia to motility and invasion beyond the hypoxic fraction in triple-negative breast cancer

Chumin Zhou, Jack T. Crusher, Kenneth Friesen, Sophie A. Twigger, Eduard Petrosyan, Graham Booker, Priya Samuel, Eileen E. Parkes, Ester M. Hammond

This study identifies TPM3 as a HIF-1-regulated protein that enhances hypoxic TNBC cell motility and invasion, and shows its potential as a therapeutic target.

npj Breast Cancer · Mar 14, 2026Peer-reviewedCancer Biology

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis

Bruno Beernaert, Rose L. Jady‐Clark, Parin Shah, Erik Ramon‐Gil, Nora M. Lawson, Zack D Brodtman, Somnath Tagore, Frederik Stihler, A. Carter, Shannique Clarke, Tong Liu, Winston M. Zhu, Juliet E. Martin, Erkin Erdal, Alistair Easton, , Eileen E. Parkes

This study shows that chromosomal instability in esophageal adenocarcinoma drives an inflammatory tumor microenvironment through a cGAS-chemokine-myeloid axis, with CXCL8 as a key mediator.

Science Advances · Mar 11, 2026Peer-reviewedCancer Biology

UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment by regulating tumour cell fate

Tatsuya Suwa, Kelly SW. Lee, Ian J. Chai, Heather O. L. Clark, David MacLean, Nicole Machado, Gonzalo Rodríguez‐Berriguete, Lolita Singh, Geoff Stuart Higgins, Ester M. Hammond, Monica M. Olcina

This study shows hypoxia induces intracellular C5aR1 via UPR, promoting tumour cell survival by regulating autophagy and apoptosis.

Cell Death and Disease · Jul 22, 2025Peer-reviewedCancer Biology

Hypoxia-activated fluorescent probes as markers of oxygen levels in plant cells and tissues

Monica Perri, Mohammad Shahneawz Khan, Antoine Wallabrègue, Viktoriia Voloboeva, Amber M. Ridgway, Edward N. Smith, Hannah R. Bolland, Ester M. Hammond, Stuart J. Conway, Daan A. Weits, Emily Flashman

The paper uses hypoxia-activated fluorescent probes to measure oxygen levels in plant cells and tissues, showing their effectiveness in detecting hypoxia in Arabidopsis thaliana.

New Phytologist · May 8, 2025Peer-reviewedPlant Biology