Author

Jacob T. Guidry

University of Wyoming

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Grant R. BowmaniD· 2 shared Ashley Park· 1 shared Nikolai MushnikoviD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBioengineering

Grant R. BowmanORCID

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2 papers

Recent·Most cited

Programmable cell differentiation in budding yeast uncouples reproductive and metabolic tasks

Jacob T. Guidry, Grant R. Bowman

The paper introduces MiSTY, a genetic platform in budding yeast that separates reproductive and metabolic tasks into distinct cell types, enabling high-yield biomanufacturing by uncoupling cell growth from product synthesis.

bioRxiv · Dec 9, 2025 · PreprintBioengineering

Microbial stem cells support productivity in dedicated factory cells in an asymmetrically dividing E. coli system

Nikolai Mushnikov, Jacob T. Guidry, Ashley Park, Grant R. Bowman

This paper describes a system in E. coli where asymmetric cell division separates reproductive stem cells from dedicated factory cells, enhancing protein productivity by reducing cytotoxicity.

bioRxiv · Oct 1, 2025 · PreprintSynthetic Biology