Grant R. Bowman

The paper introduces MiSTY, a genetic platform in budding yeast that separates reproductive and metabolic tasks into distinct cell types, enabling high-yield biomanufacturing by uncoupling cell growth from product synthesis.

This paper describes a system in E. coli where asymmetric cell division separates reproductive stem cells from dedicated factory cells, enhancing protein productivity by reducing cytotoxicity.

The paper shows that phosphorylation of CpdR by CckA controls its interaction with PopZ and its recruitment to cell poles, linking phosphosignaling to protease activity in C. crescentus.