Author

Jacqueline Ferralli

Friedrich Miescher Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Charisios D. TsiairisiD· 4 shared Panagiotis PapasaikasiD· 4 shared Clara NuningeriD· 2 shared Jaroslav FerenciD· 2 shared Sébastien A. SmallwoodiD· 2 shared Alexander V. KlimovichiD· 1 shared Jörg Wittlieb· 1 shared Marylène BonviniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersDevelopmental Biology

Charisios D. TsiairisORCID

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4 papers

Recent·Most cited

Optogenetic perturbations reveal temporal integration of Wnt signaling during pattern formation

Sera Lotte Weevers, Nicole A. Repina, Panagiotis Papasaikas, Jacqueline Ferralli, Sebastien Smallwood, Jörg Wittlieb, Alexander V. Klimovich, Charisios D. Tsiairis

This study uses optogenetics to show Hydra tissues integrate Wnt signaling over time, leading to pattern formation through cumulative transcriptional responses.

bioRxiv · Jul 8, 2026 · PreprintDevelopmental Biology

A transcription factor toggle switch determines differentiated epidermal cell identities in Hydra

Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger, Charisios D. Tsiairis

This study identifies a transcription factor toggle switch between Zic4 and Gata3 that controls epidermal cell identity in Hydra, showing their mutual antagonism determines cell fate.

Development · Aug 18, 2025Peer-reviewedDevelopmental Biology

Progressive cell fate specification in morphallactic regeneration

Clara Nuninger, Panagiotis Papasaikas, Jacqueline Ferralli, Sébastien A. Smallwood, Charisios D. Tsiairis

The paper uses single-cell RNA sequencing in Hydra to show that morphallactic regeneration involves progressive cell fate specification, similar to epimorphic regeneration.

bioRxiv · Feb 8, 2024 · PreprintDevelopmental Biology

Wnt3 expression as a readout of tissue stretching during Hydra regeneration

Jaroslav Ferenc, Panagiotis Papasaikas, Jacqueline Ferralli, Yukio Nakamura, Sébastien A. Smallwood, Charisios D. Tsiairis

The paper shows Wnt3 expression reflects tissue stretching during Hydra regeneration and can drive regeneration without mechanical input.

bioRxiv · Dec 22, 2020 · PreprintDevelopmental Biology