Author

Jai Rautela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew I. Webb· 1 shared Carolina C. de Oliveira· 1 shared Craig Harrison· 1 shared Dana S. Hutchinson· 1 shared Elliot Surgenor· 1 shared Eric Vivier· 1 shared Fernando Souza-Fonseca-Guimaraes· 1 shared Iona S. Schuster· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Andrew I. Webb

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Therapeutic blockade of Activin-A improves NK cell function and anti-tumor immunity

Jai Rautela, Laura F. Dagley, Iona S. Schuster, Soroor Hediyeh-Zadeh, Rebecca B. Delconte, Joseph Cursons, Robert Hennessy, Dana S. Hutchinson, Craig Harrison, Carolina C. de Oliveira, Eric Vivier, Andrew I. Webb, Mariapia A. Degli-Esposti, Melissa J. Davis, Nicholas D. Huntington, Fernando Souza-Fonseca-Guimaraes

This study shows Activin-A inhibits NK cell function, promotes transdifferentiation into ILC1-like cells, and suppresses anti-tumor immunity, with therapeutic blockade improving outcomes.

bioRxiv · Oct 29, 2018 · PreprintImmunology

Efficient genome editing of human natural killer cells by CRISPR RNP

Jai Rautela, Elliot Surgenor, Nicholas D. Huntington

This paper describes an efficient method for genome editing of human NK cells using CRISPR RNP and electroporation, demonstrating its effectiveness over other methods.

bioRxiv · Sep 6, 2018 · PreprintImmunology