Integrative single-cell and bulk RNA-seq analysis in human retina identified cell type-specific composition and gene expression changes for age-related macular degeneration
Yafei Lyu, Randy J. Zauhar, Nico Dana, Christianne E. Strang, Kui Wang, Shanrun Liu, Zhen Miao, Naifei Pan, Paul D. Gamlin, James A. Kimble, Jeffrey D. Messinger, Christine A. Curcio, Dwight E. Stambolian, Mingyao Li
The paper uses single-cell and bulk RNA-seq to analyze gene expression changes in human retina with AMD, identifying cell type-specific alterations.
bioRxiv · Sep 14, 2019 · PreprintGenomics