Pre-existing Immunity to Influenza Aids Ferrets in Developing Stronger and Broader Vaccine-induced Antibody Responses
Yang Ge, Yao Lu, James Allen, Tal Einav, Dennis Iziogo Nkaleke, Fengwei Bai, Andreas Handel, Ted Ross, Ye Shen
This study shows that pre-existing immunity in ferrets enhances vaccine-induced antibody responses, reducing the need for booster shots and broadening protection against homologous and heterologous influenza strains.
bioRxiv · Jan 31, 2024 · PreprintImmunology