Andreas Handel

The paper models factors influencing mpox's evolutionary emergence and finds that increased human-to-human transmissibility has a greater impact on its spread than zoonotic spillovers.

This study shows that pre-existing immunity in ferrets enhances vaccine-induced antibody responses, reducing the need for booster shots and broadening protection against homologous and heterologous influenza strains.

The paper uses mathematical models combined with experimental data to study how inoculum dose affects immune protection and morbidity, finding that an intermediate dose often balances these outcomes best.