Author

James C. Lee

Primary ORCID profile (0000-0002-7173-4875 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

James C. LeeiD2 papers · University of Illinois Chicago

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrian J. Thrasher· 1 shared Andrea Schejtman· 1 shared Annaliese O. Speak· 1 shared Anne E. Beenken· 1 shared David C. Thomas· 1 shared Elizabeth R. Dufficy· 1 shared Eve Coomber· 1 shared Fowzan S. Alkuraya· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adrian J. Thrasher

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1 paper

Recent·Most cited

EROS is required for phagocyte NADPH oxidase function in humans and its deficiency causes Chronic Granulomatous Disease.

David C. Thomas, Louis-Marie Charbonnier, Andrea Schejtman, Hasan Aldhekri, Eve Coomber, Elizabeth R. Dufficy, Anne E. Beenken, James C. Lee, Simon Clare, Annaliese O. Speak, Adrian J. Thrasher, Giorgia Santilli, Hamoud Al-Mousa, Fowzan S. Alkuraya, Talal A. Chatila, Kenneth G.C. Smith

This paper identifies EROS as a novel cause of chronic granulomatous disease by showing that EROS deficiency in humans leads to loss of gp91phox-p22phox heterodimer and impaired phagocyte function.

bioRxiv · May 28, 2018 · PreprintImmunology