Serotonin deficiency from constitutive SKN-1 activation drives pathogen apathy.
Tripti Nair, Brandy A. Weathers, Nicole L. Stuhr, James D. Nhan, Sean P. Curran
The paper shows that constitutive SKN-1 activation in C. elegans leads to serotonin deficiency, causing apathy toward pathogens and reduced survival.
Nature Communications · Sep 16, 2024Peer-reviewedGenetics