Author

James Hughes

University College LondonPrimary ORCID profile (0000-0002-5713-9738 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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James HughesiD2 papers · EcoHealth Alliance

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:dimensionality reduction· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrià CasamitjanaiD· 2 shared Alessia AtzeniiD· 2 shared Benjamin BillotiD· 2 shared Brian L. EdlowiD· 2 shared Catherine Strand· 2 shared David Lee ThomasiD· 2 shared Dorit KliemanniD· 2 shared Eleanor Robinson· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Adrià CasamitjanaORCID

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2 papers

Recent·Most cited

Fast segmentation with the NextBrain histological atlas

Oula Puonti, Jackson C. Nolan, Robert Dicamillo, Yaël Balbastre, Adrià Casamitjana, Matteo Mancini, Eleanor Robinson, Loïc Peter, Roberto Annunziata, Juri Ibrahim M. Althonayan, Shauna Crampsie, Emily Blackburn, Benjamin Billot, Alessia Atzeni, Peter Schmidt, , Juan Eugenio Iglesias

The paper introduces a fast segmentation tool for brain MRI scans using a hybrid method, achieving comparable accuracy to a Bayesian approach but with significantly reduced runtime.

Imaging Neuroscience · Jan 1, 2026Peer-reviewedNeuroscience

A next-generation, histological atlas of the human brain and its application to automated brain MRI segmentation

Adrià Casamitjana, Matteo Mancini, Eleanor Robinson, Loïc Peter, Roberto Annunziata, Juri Ibrahim M. Althonayan, Shauna Crampsie, Emily Blackburn, Benjamin Billot, Alessia Atzeni, Oula Puonti, Yaël Balbastre, Peter Schmidt, James Hughes, Jean C. Augustinack, , Juan Eugenio Iglesias

The paper introduces NextBrain, a probabilistic histological atlas of the human brain, and presents a tool for automated MRI segmentation of anatomical regions.

bioRxiv · Feb 5, 2024 · PreprintNeuroscience