Emily Blackburn

This study identifies glycogen metabolism as a key regulator of microglial function in Alzheimer's disease, showing that glycogenolysis drives microglial activation and that inhibiting it reduces Abeta uptake and functional impairment.

This study identifies impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons, linking Rab5 hyperactivation to endosomal dysfunction and ERK1/2 signalling deficits.

The paper introduces a fast segmentation tool for brain MRI scans using a hybrid method, achieving comparable accuracy to a Bayesian approach but with significantly reduced runtime.

The paper introduces NextBrain, a probabilistic histological atlas of the human brain, and presents a tool for automated MRI segmentation of anatomical regions.

The paper develops open-source tools for 3D analysis of brain dissection photographs and surface scans, achieving accurate reconstructions and segmentations comparable to MRI.