Shauna Crampsie

This study identifies that epithelial stem cell fate, not DNA damage, determines chemoradiotherapy response in rectal cancer by analyzing patient-derived organoids and using SPARTA to validate findings.

This study identifies stromal prostaglandin E2 as a key regulator of cell-fate plasticity in colorectal cancer, showing it converts chemosensitive stem cells into chemorefractory, prometastatic cells.

The paper introduces a fast segmentation tool for brain MRI scans using a hybrid method, achieving comparable accuracy to a Bayesian approach but with significantly reduced runtime.

The paper introduces NextBrain, a probabilistic histological atlas of the human brain, and presents a tool for automated MRI segmentation of anatomical regions.

This paper introduces a computational pipeline to reconstruct 3D histology of the human brain using MRI and blockface photography to overcome tissue sectioning distortions.