Author

James Murphy

University of LeedsPrimary ORCID profile (0000-0002-3046-6034 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

James MurphyiD1 paper · Yale University

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

Adrian WhitehouseiD· 1 shared Anne Cori· 1 shared Christophe Fraser· 1 shared Geoffrey Gottlieb· 1 shared Jessica M. TuckeriD· 1 shared John Mittler· 1 shared Joshua Herbeck· 1 shared Lorraine T Matandirotya· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Adrian WhitehouseORCID

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2 papers

Recent·Most cited

tRNA-derived fragments restrict KSHV lytic replication through miRNA-like repression of host pro-viral signalling networks

Lorraine T Matandirotya, James Murphy, Jessica M. Tucker, Adrian Whitehouse

This study identifies tRNA-derived fragments (tRFs) as antiviral effectors that repress KSHV lytic replication by targeting host pro-viral signalling networks.

bioRxiv · Oct 26, 2026 · PreprintMicrobiology

Evolution of HIV virulence in response to widespread scale up of antiretroviral therapy: a modeling study

Joshua Herbeck, John Mittler, Geoffrey Gottlieb, Steve Goodreau, James Murphy, Anne Cori, Michael Pickles, Christophe Fraser

This study models how HIV virulence evolves with increased antiretroviral therapy (ART) coverage, finding that universal testing and treatment may moderately increase virulence but not pose major public health concerns.

bioRxiv · Mar 17, 2016Evolutionary Biology