Jessica M. Tucker

This study identifies tRNA-derived fragments (tRFs) as antiviral effectors that repress KSHV lytic replication by targeting host pro-viral signalling networks.

This study shows that Brf1-mediated RNA polymerase III activity restricts murine gammaherpesvirus spread by enhancing host antiviral responses during low MOI infections.

This study shows that gammaherpesvirus infection leads to tRNA cleavage, producing tRNA fragments that are regulated by tRNA splicing factors and essential for viral replication.

This study investigates how HSV-1 manipulates RNA Polymerase III by increasing tRNA expression and altering transcriptional machinery interactions.

This study shows that gammaherpesvirus MHV68 infection alters the tRNAome by increasing pre-tRNA expression and affecting tRNA processing.

This study identifies MHV68 ORF36 kinase as a key factor in B2 SINE ncRNA activation during gammaherpesvirus infection, linking it to chromatin modification changes.