Adrian Whitehouse

This study identifies tRNA-derived fragments (tRFs) as antiviral effectors that repress KSHV lytic replication by targeting host pro-viral signalling networks.

This study shows that EMG1 methyltransferase activity regulates ribosome occupancy at KSHV uORFs, affecting viral protein expression and infectious virus production.

This study shows HOP/STIP1 is essential for KSHV lytic replication in primary effusion cell lines.

This study shows virus-induced paraspeckle-like structures are critical for viral replication and contribute to genomic instability during KSHV and EBV infections.

The paper examines XIST RNA-protein interactions across mammals with different early pregnancy morphologies, finding conserved binding partners but species-specific binding preferences.

The paper identifies lncRNAs that interact with the translation machinery during neuronal differentiation and shows some produce peptides that affect neurite length.